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Assessment of single-trial evoked brain oscillations targeted by transcranial alternating current stimulation using optically-pumped magnetometry
Dr. Vincent JonanyDone
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Sponge EEG is equivalent regarding signal quality, but faster than routine EEG
Dr. med. Justus MarquetandDone
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Motor reorganization after stroke: From pathophysiology to treatment strategies
Caroline TscherpelDone
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Optically pumped magnetometers for neuroscience - disruptive or evolutionary?
Dr. Tilmann Sander-ThömmesDone
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Introduction
Sebastian CarstensDone
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Optimal closed loop cortical stimulation therapy in patients with focal epilepsy in primary motor cortex
Geertjan Huiskamp, PhDDone
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Measuring the Effects of Amazonian Ayahuasca Retreats with EEG: The Challenges and Rewards of Naturalistic Neuroscience
Caspar MontgomeryDone
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EEG microstates as a tool to capture brain network dynamics
Prof. Dr. Christoph M. MichelDone
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Non-invasive brain stimulation in supporting motor abilities in stroke patients and healthy people
Prof. Dr. Jitka VeldemaDone
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Transcranial magnetic stimulation - mapping, targeting, and computational modeling
Prof. Dr. Thomas R. KnöscheDone
Peter Uhlhaas obtained a BSc and PhD in Psychology from the University of Stirling, Scotland. He was a visiting researcher at Weill Medical College, Cornell University, New York (2001-2002), before joining the Department of Neurophysiology (Head: Prof. Wolf Singer), Max-Planck Institute (MPI) for Brain Research in Frankfurt, Germany. At the MPI, he became a group leader in 2006, investigating the neurophysiology of cognitive dysfunctions in schizophrenia. Peter joined the Institute of Neuroscience and Psychology, University of Glasgow, in 2012 where he is a principal investigator at the Centre for Cognitive Neuroimaging. He has published 120 articles in internationally high-ranking journals (Nature Rev Neuroscience, Neuron, PNAS, JAMA Psychiatry). In 2019, he became Professor for Early Detection and Diagnosis of Mental Disorders at the Department of Child and Adolescent Pschiatry Charité-Universitätsmedizin Berlin. His work is supported by the Medical Research Council, Einstein Foundation, German Research Foundation and Wellcome Trust.language. Since 2021 he has been working on his doctoral thesis entitled: “Language mapping in patients with parenchymatous tumor in language eloquent areas.”
There is converging evidence that 40-Hz Auditory Steady-State Responses (ASSRs) are robustly impaired in schizophrenia and could constitute a potential biomarker for characterizing circuit dysfunctions as well as enable early detection and diagnosis. Here, I will summarize findings from electro- and magnetoencephalographic studies in participants at clinical high risk for psychosis, patients with first episode psychosis as well as patients with 22q11.2 deletion syndrome to identify the pattern of deficits across illness stages, the relationship with clinical variables, and the prognostic potential. Finally, data on genetics and developmental modifications will be reviewed, highlighting the importance of late modifications of 40-Hz ASSRs during adolescence, which are closely related to the underlying changes in GABA (gamma-aminobutyric acid) interneurons. Together, our review suggests that 40-Hz ASSRs may constitute an informative electrophysiological approach to characterize circuit dysfunctions in psychosis that could be relevant for the development of mechanistic biomarkers.