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Electrophysiological characterization enables mechanistic insight beyond observable behavior
Location: Alte Kornkammer - 1/15/26, 4:00 PM - 1/15/26, 4:30 PM (Europe/Berlin) (30 minutes)
Electrophysiological characterization enables mechanistic insight beyond observable behavior
Robert Fleischmann, MD, PhD
Physician/Research Associate at Universität Greifswald
Robert Fleischmann, MD, PhD
Physician/Research Associate at Universität Greifswald

Robert Fleischmann obtained a post-doctoral lecturing qualification (Habilitation) in Neurology at the University Medicine Greifswald, Germany, where he is Managing Senior Physician at the Department of Neurology, Senior Physician at the Headache Centre and Movement Disorders Section, and Deputy Medical Director of the Delirium Prevention Task Force. He earned his doctorate in Human Medicine at Charité – University Medicine Berlin, after which he achieved a master’s degree in Health Business Administration, at FAU Erlangen-Nürnberg, Germany.

Prof. Fleischmann was recently awarded the Theo and Friedl Schöller Award for Geriatric Medicine and received the Oral Presentation Award at the European Delirium Conference in 2024, the Poster Prize at the German Pain Congress in 2022, and the Sokya Award for Pain Research from the German Migraine and Headache Society in 2020.

Clinical syndromes such as delirium demonstrate that similar phenotypes can arise from distinct biological mechanisms. Novel EEG technologies enable the identification of endotypes that reflect network-level dysfunction rather than surface behavior. The combination of electrophysiological and neuroimmunological methods reveals mechanistic pathways such as (neuro-)inflammation that often show ambiguous associations with the clinical phenotype. Our data indicate that the investigation of endotypes provides a closer link to underlying pathophysiology and may therefore advance both the understanding of complex brain disorders and the development of targeted therapeutic strategies.