Electrophysiological measures as biomarkers of disease progression and outcome in psychoses
11/3/22, 11:50 AM - 11/3/22, 12:20 PM (Europe/Amsterdam) (30 minutes)

Prof. Giorgio Di Lorenzo
Associate Professor of Psychiatry, Laboratory of Psychophysiology and Cognitive Neuroscience, Department of Systems Medicine University of Rome Tor Vergata
Associate Professor of Psychiatry, Laboratory of Psychophysiology and Cognitive Neuroscience, Department of Systems Medicine University of Rome Tor Vergata

Giorgio Di Lorenzo, M.D., Ph.D., is an Associate Professor of Psychiatry and directs the Laboratory of

Psychophysiology and Cognitive Neuroscience (PsyCoNeLab), at the Department of Systems Medicine of the University of Rome Tor

Vergata. The main field of interest is in the clinical application of EEG recording as a tool for the investigation of the pathophysiology

of brain connectivity in mental disorders (mainly psychosis, autism, and trauma-related disorders), as well as the examination

of neurophysiological changes induced by psychopharmacological, psychotherapeutic, brain electromagnetic stimulation and

modulation, and rehabilitative treatments.


The use of electroencephalography (EEG) as a tool to discriminate people with or without psychosis has failed until now.

The heterogeneity in psychopathological features and outcomes in subjects with psychosis has led to the search for biomarkers that

could improve the diagnostic and prognostic processes. In recent years, research in psychosis has highlighted how abnormalities of

electrophysiological indices could be associated with clinical features, the outcome, and the risk of psychosis. Within this frame, Di

Lorenzo will present the results of recent, large, and multicenter studies that use EEG indices in subjects with psychosis, discussing their

use as potential biomarkers. Di Lorenzo will also offer a critical viewpoint for translating EEG research into clinical practice to facilitate the

early diagnosis and identify markers of progression, prognosis, and treatment of this severe illness.