-
Optimizing TMS Targeting and Treatment Response in Depression: Insights from Functional Connectivity and Induced Brain Activity Effects
Romain Duprat, PhDDone
-
How to use biomarkers in closed-loop neuromodulation
Marom Bikson, PhDDone
-
Personalized therapeutic brain-stimulation with real-time EEG-synchronized TMS
Christoph Zrenner, MDDone
-
Precision in TMS motor mapping and neuromodulation targeting: Clinical relevance and updates
Dylan Edwards, PhDDone
-
Brain maturation in children with autism spectrum disorder – overly rapid followed by too slow
J. Christopher Edgar, PhDDone
-
High-Intensity Targeted HD-tDCS for Motor Skill Learning
Gavin HsuDone
-
Toward Enhancing Cognition in Real Time
John Medaglia, PhDDone
-
Magnetoencephalography (MEG): Considerations vs. EEG for Clinical and Research Applications – A Moving Target?
Timothy P.L. RobertsDone
-
Clinical Applications of EEG in Children
Sudha Kilaru Kessler, MD, MSCEDone
-
State of the technology / What ANT does / What products are on the horizon
Dr. Frank ZanowDone
My research interests are identifying antecedents of brain injury in critically ill infants using multimodal monitoring. We use a battery of physiological measures such as EEG, heart rate from ECG, oxygen saturation, cerebrovascular signals from near-infrared spectroscopy, and blood pressure indwelling arterial line. The commonly used physiological variables include heart rate variability, cerebral pressure autoregulation, power spectral metrics of EEG at the scalp and source levels, functional connectivity identified using EEG sources, and relating the connectivity metrics to neurodevelopmental outcomes. Our clinical cohorts include preterm infants, hypoxic-ischemic encephalopathy in term newborns, and congenital heart disease infants.
Our group has successfully demonstrated the association between impairment in cerebral pressure autoregulation and higher incidences of brain injury in critically ill infants. Also, we have developed predictive models using heart rate variability to predict the outcome of term newborns undergoing therapeutic hypothermia for hypoxic-ischemic encephalopathy. Before embarking on pediatric physiological signal analysis, I worked on maternal-fetal physiology acquired using magnetobiometry. We have studied the development of the fetal autonomic nervous system and fetal brain function. We have also studied the association between uterine contraction and the nature of labor using maternal myometrial activity acquired using magnetometry.